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Actavis Promathazine Syrup

Actavis Promathazine Syrup analgesics, including codeine, exert their primary effects on the central nervous system and gastrointestinal tract.

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Actavis Promethazine Syrup, often referred to simply as “lean” or “purple drank,” has gained notoriety in popular culture, but what exactly is it, and how does it work? In this article, we’ll explore the uses, risks, and legal aspects of Actavis Promethazine Syrup.

Introduction to Actavis Promethazine Syrup

Actavis Promethazine Syrup is a prescription medication that contains codeine, promethazine, and other ingredients. It is primarily used as a cough suppressant and antihistamine but is also known for its sedative effects.

What is Actavis Promethazine Syrup?


The main active ingredients in Actavis Promethazine Syrup are codeine phosphate, a narcotic cough suppressant, and promethazine hydrochloride, an antihistamine. It also contains inactive ingredients such as alcohol and high fructose corn syrup.


Actavis Promethazine Syrup is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergies or the common cold. It is also used to treat symptoms of motion sickness and to induce sedation before medical procedures.

Uses of Actavis Promethazine Syrup

Treatment of Cough

Actavis Promethazine Syrup is commonly prescribed to suppress coughing, particularly when other over-the-counter cough medicines have not been effective. It works by suppressing the cough reflex in the brain.

Sedative Effects

Due to its sedative properties, Actavis Promethazine Syrup is sometimes used off-label to induce relaxation and alleviate anxiety. However, it should only be used for this purpose under the guidance of a healthcare professional.

Recreational Use

Unfortunately, Actavis Promethazine Syrup has gained popularity among certain demographics for its recreational effects when consumed in large quantities. This misuse can lead to serious health consequences and even overdose.

Side Effects and Risks

Drowsiness and Dizziness

One of the most common side effects of Actavis Promethazine Syrup is drowsiness and dizziness, which can impair judgment and motor skills. It is essential to avoid driving or operating heavy machinery while under the influence of this medication.

Respiratory Depression

In high doses, Actavis Promethazine Syrup can cause respiratory depression, a potentially life-threatening condition characterized by slowed or shallow breathing. This risk is particularly significant when the medication is abused or combined with other substances like alcohol or opioids.

Potential for Abuse and Addiction

Actavis Promethazine Syrup contains codeine, a narcotic opioid with a high potential for abuse and addiction. Prolonged use or misuse of this medication can lead to physical dependence and withdrawal symptoms upon discontinuation.

Legality and Regulation

Due to its potential for abuse and addiction, Actavis Promethazine Syrup is a controlled substance regulated by government authorities. It is illegal to possess or distribute this medication without a valid prescription.

Availability and Purchase

Actavis Promethazine Syrup is available by prescription only and should only be obtained from licensed healthcare providers and pharmacies. Purchasing this medication without a prescription or from illicit sources is illegal and unsafe.


While Actavis Promethazine Syrup can be an effective treatment for cough and respiratory symptoms when used as directed, it also carries significant risks, particularly when misused or abused. It is essential to use this medication responsibly and under the guidance of a healthcare professional to avoid adverse effects and complications.


  1. Can Actavis Promethazine Syrup be used to treat allergies?
    • Yes, Actavis Promethazine Syrup is sometimes prescribed to relieve symptoms of allergies, such as sneezing and runny nose.
  2. Is Actavis Promethazine Syrup safe for children?
    • Actavis Promethazine Syrup should not be used in children under the age of 12 due to the risk of serious side effects, including respiratory depression.
  3. What should I do if I miss a dose of Actavis Promethazine Syrup?
    • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
  4. Can I drink alcohol while taking Actavis Promethazine Syrup?
    • Drinking alcohol while taking Actavis Promethazine Syrup can increase the risk of side effects such as drowsiness and dizziness. It is advisable to avoid alcohol consumption while using this medication.
  5. How long does it take for Actavis Promethazine Syrup to work?
    • Actavis Promethazine Syrup typically begins to work within 30 minutes to an hour after ingestion, with peak effects occurring within 2 to 4 hours. However, individual response may vary.

Actavis Promathazine Syrup